Abstract
WHEN a dog brain is isolated from all structures except the skull and perfused with blood from a compatible donor animal, it has properties which make it especially useful for metabolic studies of neural tissue1,2. In all studies conducted with the isolated dog brain, the EEG has been used as a measure of the viability of the isolated and extra-corporeally maintained brain. There remains the question of whether the isolated brain is functioning sufficiently well to respond to normal external stimuli.
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References
Gilboe, D. D., Cotanch, W. W., and Glover, M. B., Nature, 206, 94 (1965).
Gilboe, D. D., Glover, M. B., and Cotanch, W. W., Amer. J. Physiol., 213, 11 (1967).
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BLOMQUIST, A., GILBOE, D. Auditory and Somatic Sensory Responses evoked in the Cerebral Cortex of the Isolated Dog Brain. Nature 227, 409 (1970). https://doi.org/10.1038/227409a0
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DOI: https://doi.org/10.1038/227409a0
