Abstract
THE method developed by Mishell and Dutton1 for the in vitro stimulation of an apparently primary response to red cell antigens offers advantages over in vivo experiments in analysing the cellular basis of the immune response. The possible uses of the in vitro system would be much increased were it possible to get reproducible responses to a well defined hapten.
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References
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Mitchison, N. A., Rajewsky, K., and Taylor, R. B., in Developmental Aspects of Antibody Formation and Structure (edit. by Sterzl, J., and Riha, O. I.) (Academic Press, New York, in the press).
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TROWBRIDGE, I., LENNOX, E. & PORTER, R. Induction in vitro of Hapten Specific Plaque Forming Cells. Nature 228, 1087–1089 (1970). https://doi.org/10.1038/2281087a0
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DOI: https://doi.org/10.1038/2281087a0
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