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Mode of Action of 5-Hydroxytryptamine on Isolated Rat Vas Deferens

Nature volume 228, pages 564–565 (1970)Cite this article

Abstract

IT has been suggested that 5-hydroxytryptamine (serotonin) might cause the rat vas deferens to contract by interacting directly with the α-adrenergic receptors in the organ1. We found that vas deferens isolated from reserpinized rats could not respond to serotonin, so we have investigated the mode of action of serotonin on this preparation, and compared it with the action of tvramine.

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References

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Authors and Affiliations

  1. Department of Chemical Pharmacology, Kyorin Chemical Laboratory, Tokyo, Japan

    K. NISHINO & T. IRIKURA

  2. Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan

    I. TAKAYANAGI

Authors
  1. K. NISHINO
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  2. T. IRIKURA
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  3. I. TAKAYANAGI
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NISHINO, K., IRIKURA, T. & TAKAYANAGI, I. Mode of Action of 5-Hydroxytryptamine on Isolated Rat Vas Deferens. Nature 228, 564–565 (1970). https://doi.org/10.1038/228564a0

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  • DOI: https://doi.org/10.1038/228564a0

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