Abstract
By modulating the structural features of a series of haptens and observing their strengths of interaction with antibody, conclusions are drawn which cast doubt on previous interpretations of hapten–subsite fitting.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kabat, E. A., J. Immunol., 84, 82 (1960).
Kabat, E. A., Structural Concepts in Immunology and Immunochemistry (Holt, Rinehart and Winston, New York, 1968).
Sage, H. J., Deutsch, G. F., Fasman, G. D., and Levine, L., Immunochemistry, 1, 133 (1964).
Arnon, R., Sela, M., Yaron, A., and Sober, H. A., Biochemistry, 4, 948 (1965).
Schechter, L., Schechter, B., and Sela, M., Biochim. Biophys. Acta, 127, 438 (1966).
Van Vunakis, H., Kaplan, J., Lehrer, H. I., and Levine, L., Immunochemistry, 3, 393 (1966).
Goodman, J. W., Immunochemistry, 6, 139 (1969).
Haimovich, J., Schechter, I., and Sela, M., Europ. J. Biochem., 7, 537 (1969).
Schechter, B., Schechter, I., and Sela, M., J. Biol. Chem., 245, 1438 (1970).
Schechter, L., Israel J. Med. Sci., 6, 441 (1970).
Phillips, D. C., Sci. Amer., 215, 78 (1966).
Sharon, N., and Chipman, D., Science, 165, 454 (1969).
Schechter, I., and Berger, A., Biochem. Biophys. Res. Commun., 27, 157 (1967).
Schechter, I., and Berger, A., Biochem. Biophys. Res. Commun., 32, 898 (1968).
Berger, A., and Schechter, I., Phil. Trans. Roy. Soc., B, 257, 249 (1970).
Berger, A., Schechter, I., Benderli, H., and Kurn, N., in Proc. Tenth Europ. Symp. on Peptides (Abano, Italy, 1969) (North-Holland, Amsterdam, in the press).
Abramowitz, N., Schechter, I., and Berger, A., Biochem. Biophys. Res. Commun., 29, 862 (1967).
Cuatrecasas, P., Wilchek, M., and Anfinsen, C. B., Science, 162, 1491 (1968).
Morihara, K., Oka, T., and Tsuzuki, H., Arch. Biochem. Biophys., 135, 311 (1969).
Thoma, J. A., Brothers, C., and Spradlin, J., Biochemistry, 9, 1768 (1970).
Robbins, J. B., Haimovich, J., and Sela, M., Immunochemistry, 4, 11 (1967).
Schechter, I., and Berger, A., Biochemistry, 5, 3362 (1966).
Anderson, G. W., Zimmerman, J. E., and Callahan, F. M., J. Amer. Chem. Soc., 86, 1839 (1964).
Pressman, D., and Grossberg, A. L., The Structural Basis of Antibody Specificity (Benjamin, New York, 1968).
Karush, F., J. Amer. Chem. Soc., 78, 5519 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SCHECHTER, I. Mapping of the Combining Sites of Antibodies specific for Poly-L-alanine Determinants. Nature 228, 639–641 (1970). https://doi.org/10.1038/228639a0
Received:
Issue date:
DOI: https://doi.org/10.1038/228639a0
