Abstract
Similarities between the binding properties of cytochrome c and the permeability properties of mitochondria suggest that cytochrome c may be a transport carrier of the inner mitochondrial membrane. Cytochrome c could be the basis of a mechanism by which mitochondrial activities are regulated by the metabolic state of the cell. Variations in the structure of cytochromes c from different species may result from evolutionary selection for particular ion-binding properties.
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MARGOLIASH, E., BARLOW, G. & BYERS, V. Differential Binding Properties of Cytochrome c: Possible Relevance for Mitochondrial Ion Transport. Nature 228, 723–726 (1970). https://doi.org/10.1038/228723a0
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DOI: https://doi.org/10.1038/228723a0
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