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Chromosome Size and Hypodiploidy

Abstract

IN chromosome preparations from peripheral lymphocytes a certain number of aneuploid metaphases are usually found (about 10–20 per cent hypodiploid and 1–2 per cent hyperdiploid chromosome sets). These aberrations are usually the result of technical artefacts. In cases where a true numerical chromosomal aberration can be expected these unavoidable artefacts can cause erroneous results.

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References

  1. Pegoraro, L., Rovera, G., Masera, P., and Gavosto, F., Lancet, ii, 618 (1967).

  2. Neurath, P., DeRemer, K., Bell, B., Jarvik, L., and Kato, T., Nature, 225, 281 (1970).

    Article  ADS  CAS  Google Scholar 

  3. Court Brown, W. M., Buckton, K. E., Jacobs, P. A., Tough, I. M., Kuenssberg, E. V., and Knox, J. D. E., Chromosome Studies on Adults (Cambridge Univ. Press, London, 1966).

    Google Scholar 

  4. Jacobs, P. A., and Court Brown, W. M., Nature, 212, 823 (1966).

    Article  ADS  CAS  Google Scholar 

  5. Zang, K. D., and Back, E., Lancet, ii, 1423 (1967).

  6. Zang, K. D., and Back, E., Cytogenetics, 7, 455 (1968).

    Article  CAS  Google Scholar 

  7. Back, E., and Zang, K. D., Humangenetik, 8, 47 (1969).

    CAS  PubMed  Google Scholar 

  8. Zang, K. D., and Singer, H., Nature, 216, 84 (1967).

    Article  ADS  CAS  Google Scholar 

  9. Singer, H., and Zang, K. D., Humangenetik, 9, 172 (1970).

    CAS  PubMed  Google Scholar 

  10. De Grouchy, J., and De Nava, C., Ann. Intern. Med., 69, 381 (1968).

    Article  CAS  Google Scholar 

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ZANG, K., ZANKL, H. Chromosome Size and Hypodiploidy. Nature 228, 778–779 (1970). https://doi.org/10.1038/228778a0

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