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Biological Sciences: Effect of Prostaglandin on E1 on Clot Retraction

Abstract

ONE of the many properties of prostaglandin E1 (PGE1) is that it inhibits the aggregation of blood platelets in plasma at µg/ml. platelet-rich plasma1–3, and of ADP-induced adhesiveness at the same low concentration1,2. Emmons et al.1 have also shown that platelet plug formation is prevented in vivo during infusion of PGE1. Because of this we decided to investigate the effect of PGE1 on clot retraction.

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References

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MÜRER, E. Biological Sciences: Effect of Prostaglandin on E1 on Clot Retraction. Nature 229, 112–113 (1971). https://doi.org/10.1038/229112a0

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