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Chromatid Disjunction in Unfertilized Ageing Oocytes

Nature volume 233, pages 191–193 (1971)Cite this article

Abstract

AGEING mammalian oocytes, which have spent longer than the optimum time in the oviduct without being fertilized, may, after fertilization, give rise to abnormal embryos in which aneuploidy is frequent1. We have now observed a change in the organization of the chromosomes of ageing secondary oocytes of mice, which may account for the occurrence of aneuploidy at the second meiotic division.

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References

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  1. Department of Anatomy, Cornell University Medical College, 1300 York Avenue, New York, New York, 10021

    TOBY C. RODMAN

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  1. TOBY C. RODMAN
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RODMAN, T. Chromatid Disjunction in Unfertilized Ageing Oocytes. Nature 233, 191–193 (1971). https://doi.org/10.1038/233191a0

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  • DOI: https://doi.org/10.1038/233191a0

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