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Effect of Hormonal State on Cell Number and Functional Maturation of the Brain

Abstract

IT is known that thyroid administration interferes with postnatal cell formation1 and affects the functional maturation of the brain2,3. Glucocorticoids also inhibit cell division in the brain4–6, but the ultimate behavioural consequences of treatment during infancy with thyroid and with adrenocortical hormones seem to be different2,7. In attempting to understand these differences a study was made of the effects of cortisol on postnatal cell formation in the rat brain. Further details are given elsewhere8.

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BALÁZS, R., COTTERRELL, M. Effect of Hormonal State on Cell Number and Functional Maturation of the Brain. Nature 236, 348–350 (1972). https://doi.org/10.1038/236348a0

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