Abstract
CAPACITATION of hamster1,2 and mouse3 sperms in vitro has been achieved in the presence of, or after treatment by, follicular fluid. In vitro fertilization of mouse eggs by epididymal sperms4,5 can take place in a synthetic medium without follicular fluid. These findings indicate that the current concept of capacitation should be modified. Confirmation of the results might be found in rabbit ova and sperms, because the capacitation of rabbit sperms is generally accepted as necessary for fertilization.
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OGAWA, S., SATOH, K., HAMADA, M. et al. In vitro Culture of Rabbit Ova fertilized by Epididymal Sperms in Chemically Defined Media. Nature 238, 270–271 (1972). https://doi.org/10.1038/238270a0
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DOI: https://doi.org/10.1038/238270a0
