Figure 1

Rhodamine exclusion by control and MDR-1-transduced FDCP-mix clones. Data shown are derived from four control (parental FDCP-mix (a), and three tNGFR transduced clones (b–d)) and four MDR-1-transduced clones (e–h). Solid histograms indicate rhodamine fluorescence when no efflux time was allowed prior to FACS analysis. Open histograms indicate rhodamine fluorescence following efflux.