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Rapid Generation of Whole-Body Radioautograms with Microchannel Plate Electron Image Amplifiers

Nature volume 242, pages 523–525 (1973)Cite this article

Abstract

WHOLE-BODY radioautography is a useful method for studying the distribution of radio-labelled compounds among all the organs and tissues of an experimental animal1–4. Rapid excretion of radio-labelled drug, low energy radiation as in tritium, or low specific activity of isotopes often require weeks or months of exposure of emulsion to whole-body sections for the generation of radioautographic data. Here we describe a new simple technique for efficient, rapid generation of radioautographic images, using a microchannel plate electron image amplifier to detect electrons emitted from the surface of labelled tissue.

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Author information

Authors and Affiliations

  1. Arthur D. Little, Inc., Cambridge, Massachusetts, 02140

    R. H. LISS & D. B. LINDSAY

  2. Bendix Corporation, Southfield, Michigan, 48075

    C. E. CATCHPOLE

Authors
  1. R. H. LISS
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  2. D. B. LINDSAY
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  3. C. E. CATCHPOLE
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LISS, R., LINDSAY, D. & CATCHPOLE, C. Rapid Generation of Whole-Body Radioautograms with Microchannel Plate Electron Image Amplifiers. Nature 242, 523–525 (1973). https://doi.org/10.1038/242523a0

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  • DOI: https://doi.org/10.1038/242523a0

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