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Positional Information in Chick Limb Morphogenesis

Nature volume 244, pages 492–496 (1973)Cite this article

Abstract

Pattern formation by the cells of a growing organism depends on coordination of changes in space and time. Evidence is presented here for the control of morphogenesis by positional information specified by an autonomous timing mechanism that operates in a “progress zone” at the tip of the limb bud.

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Authors and Affiliations

  1. Department of Biology as Applied to Medicine, The Middlesex Hospital Medical School, London, W1P 6DB

    D. SUMMERBELL, J. H. LEWIS & L. WOLPERT

Authors
  1. D. SUMMERBELL
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  2. J. H. LEWIS
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  3. L. WOLPERT
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SUMMERBELL, D., LEWIS, J. & WOLPERT, L. Positional Information in Chick Limb Morphogenesis. Nature 244, 492–496 (1973). https://doi.org/10.1038/244492a0

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  • DOI: https://doi.org/10.1038/244492a0

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