Abstract
ANTIBODY synthesis is known to result from cooperation between antigen specific bursal equivalent (B) cells and thymus-dependent (T) cells1,2. When hapten-protein conjugates are used as antigens, the T cells recognize the carrier protein determinants and the B cells produce the hapten-specific antibody3,4.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Miller, J. F. A. P., and Mitchell, G. F., Transplant. Rev., 1, 3 (1969).
Claman, H. N., and Chaperon, E. A., Transplant. Rev., 1, 92 (1969).
Rajewsky, K., Schirrmacher, V., Nase, S., and Jerne, N. K., J. expl. Med., 129, 1131 (1969).
Mitchison, N. A., Eur. J. Immun., 1, 10 (1971).
Leskowitz, S., J. expl. Med., 117, 909 (1963).
Nauciel, C., and Raynaud, M., Eur. J. Immun., 1, 257 (1971).
Alkan, S. S., Nitecki, D. E., and Goodman, J. W., J. Immun., 107, 353 (1971).
Hanna, N., and Leskowitz, S., Cellular Immunol. (in the press).
Alkan, S. S., Williams, E. B., Nitecki, D. E., and Goodman, J. W., J. expl. Med., 135, 1228 (1972).
Leskowitz, S., Science N.Y., 155, 350 (1967).
Bloch, K., Kourilsky, F. M., Ovary, Z., and Benacerraf, B., J. expl. Med., 117, 969 (1963).
Ovary, Z., and Benacerraf, B., Proc. Soc. expl. Biol. Med., 114, 72 (1963).
Leskowitz, S., Richerson, H. B., and Schwarts, H. J., Immunochemistry, 7, 949 (1970).
Feldmann, M., and Basten, A., Eur. J. Immun., 2, 213 (1972).
Schwartz, R. S., Leskowitz, S., and Gottlieb, A. A., Immunochemistry, 9, 601 (1972).
Smyth, R. D., and Maurer, P. H., J. Immun., 108, 1420 (1972).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HANNA, N., BHAN, I. & LESKOWITZ, S. Hapten-specific Helper Effects in Antibody Formation. Nature 244, 569–570 (1973). https://doi.org/10.1038/244569a0
Received:
Revised:
Issue date:
DOI: https://doi.org/10.1038/244569a0
