Abstract
THERE is still no adequate explanation for the fact that the placenta, which is foetal in origin and therefore allogeneic in the mother, is not rejected during pregnancy. A question of fundamental importance is whether human trophoblast cells possess HL-A or ABO antigens. Evidence so far is conflicting1–4. We present evidence which suggests that blood group A antigens may be present on human trophoblast cells, but at low surface density.
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References
Theide, H. A., Choate, J. W., Gardner, H. H., and Santay, H., J. exp. Med., 121, 1039 (1965).
Gross, S. J., Am. J. Obstet. Gynec., 95, 1149 (1966).
Seigler, H. L., and Metzgar, R. S., Transplantation, 9, 478 (1970).
Loke, Y. W., Joysey, V. C., and Borland, R., Nature, 232, 403 (1971).
Coombs, R. R. A., Bedford, D., and Rouillard, L. M., Lancet, i, 461 (1956).
Sell, K. W., Mori, W., Rack, J. H., Gurner, B. W., and Coombs, R. R. A., Br. J. exp. Path., 50, 413 (1969).
Kirby, D. R. S., Billington, W. D., Bradbury, S., and Goldstein, D. J., Nature, 204, 548 (1964).
Currie, G. A., Van Doorninck, W., and Bagshawe, K. D., Nature, 219, 191 (1968).
Coombs, R. R. A., and Franks, D., in Progress in Allergy (edit. by Kallos, P., and Waksman, B. H.), 13, 174 (Karger, Basel, 1969).
Anderson, J. M., Nature's Transplant (Butterworth, London, 1972).
Linscott, W. D., Nature, 228, 824 (1970).
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LOKE, Y., BALLARD, AC. Blood Group A Antigens on Human Trophoblast Cells. Nature 245, 329–330 (1973). https://doi.org/10.1038/245329a0
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DOI: https://doi.org/10.1038/245329a0


