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Some behavioural signs of morphine withdrawal blocked by conditional stimuli

Abstract

IT has been suggested that the opiate addict gets pleasure both from the physiological effects of the drug and from the complex of environmental stimuli associated with obtaining and administering the drug. These latter stimuli achieve their control over behaviour by a conditioning process and can therefore, in theoretical terms, be considered as conditional stimuli in the Pavlovian sense. Wilder1 proposes that the repeated occurrence of certain exteroceptive stimuli which accompany the interoceptive stimulation induced by the opiate, results in conditioning of the environment to the drug state.

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TYE, N., IVERSEN, S. Some behavioural signs of morphine withdrawal blocked by conditional stimuli. Nature 255, 416–418 (1975). https://doi.org/10.1038/255416a0

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