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Actin–tubulin homology revisited

Abstract

THERE seems to be a principle underlying all eukaryotic motile systems. Movement, whether it be muscular, ciliar, flagellar or cytoplasmic, is apparently realised through the ATP-dependent sliding interaction of fibrillar proteins. This has raised the controversial question of whether the corresponding proteins from different systems are in fact homologues. Indeed, many proteins involved in motility have been isolated and characterised and have been reported as actins1–5.

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ALICEA, H., RENAUD, F. Actin–tubulin homology revisited. Nature 257, 601–602 (1975). https://doi.org/10.1038/257601a0

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