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Regulation of cell cycle stage-specific transcription of histone genes from chromatin by non-histone chromosomal proteins

Nature volume 257, pages 764–767 (1975)Cite this article

Abstract

RNA transcripts from chromatin of S phase but not G1 cells contain histone-specific sequences. Chromatin reconstituted with S phase non-histone chromosomal proteins transcribes histone messenger RNA sequences whereas chromatin reconstituted with G1 non-histone proteins does not. These results suggest that transcription of histone genes is regulated during the cell cycle and that non-histone proteins have a key role in this regulation.

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Authors and Affiliations

  1. Department of Biochemistry, University of Florida, Gainesville, Florida, 32610

    Gary Stein, William Park, Cary Thrall, Rusty Mans & Janet Stein

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  1. Gary Stein
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  2. William Park
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  3. Cary Thrall
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  4. Rusty Mans
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  5. Janet Stein
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Stein, G., Park, W., Thrall, C. et al. Regulation of cell cycle stage-specific transcription of histone genes from chromatin by non-histone chromosomal proteins. Nature 257, 764–767 (1975). https://doi.org/10.1038/257764a0

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