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Inversion of levels of human T and B cells in early pregnancy

Abstract

CELL-MEDIATED immunity has been shown to be decreased during pregnancy1,2. Finn et al.3 suggested that the cause may be a decrease in the number of T cells; however, levels of T cells were unchanged in women in the third trimester of pregnancy4. In addition, the normal number of B cells was found in women who had been pregnant for at least 6 months5. Gergely et al.6 also found normal levels of T and B lymphocytes in women between 34 and 36 weeks of gestation. So far no change has been shown in T- and B-cell levels during the latter half of pregnancy.

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STRELKAUSKAS, A., WILSON, B., DRAY, S. et al. Inversion of levels of human T and B cells in early pregnancy. Nature 258, 331–332 (1975). https://doi.org/10.1038/258331a0

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