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Confusion between specific and nonspecific binding of carcinoembryonic antigen and blood-group antigens by eluted antibody preparations
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  • Published: 22 January 1976

Confusion between specific and nonspecific binding of carcinoembryonic antigen and blood-group antigens by eluted antibody preparations

  • GEOFFREY TAYLOR1 &
  • DAVID L. J. FREED1 

Nature volume 259, pages 237–239 (1976)Cite this article

  • 434 Accesses

  • 9 Citations

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Abstract

CROSS reactivity between carcinoembryonic antigen (CEA) and blood-group antigens is inferred from the observation that many human sera can bind labelled CEA. This is more common with sera of blood group O or B (that is containing anti-A antibodies), and binding may sometimes be inhibited by absorption of the sera with group A erythrocytes1,2.

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Author information

Authors and Affiliations

  1. Immunology Laboratory, University of Manchester, Manchester, M13 9PT, UK

    GEOFFREY TAYLOR & DAVID L. J. FREED

Authors
  1. GEOFFREY TAYLOR
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  2. DAVID L. J. FREED
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Cite this article

TAYLOR, G., FREED, D. Confusion between specific and nonspecific binding of carcinoembryonic antigen and blood-group antigens by eluted antibody preparations. Nature 259, 237–239 (1976). https://doi.org/10.1038/259237a0

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  • Received: 17 October 1975

  • Accepted: 27 November 1975

  • Issue date: 22 January 1976

  • DOI: https://doi.org/10.1038/259237a0

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