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A recombinant in the major histocompatibility complex of the rat

Nature volume 266, pages 362–364 (1977)Cite this article

Abstract

WE report here a recombinant in the major histocompatibility complex (MHC) of the rat, and describe the properties of alloantisera directed at the recombined portions of one haplotype. The results are compatible with a structure for the rat MHC more closely resembling that of man than that of the mouse.

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References

  1. Palm, J. Trans. Proc. 3, 169 (1971).

    CAS  Google Scholar 

  2. Stark, O., Kren, V. & Günther, E. Trans. Proc. 3, 165 (1971).

    CAS  Google Scholar 

  3. Parish, C. R. & Hayward, J. A. Proc. R. Soc. B, 187, 65 (1974).

    Article  ADS  CAS  Google Scholar 

  4. Amos, D. B., Zumpft, M. & Armstrong, P. Transplantation 1, 270 (1963).

    Article  CAS  Google Scholar 

  5. Graziano, K. D. & Edidin, M. in Proc. Symp. Immunogenet. H–2 System (eds Lengerova, A. & Vojtiskova, M.) 251–256 (Karger, Basel, 1971).

    Google Scholar 

  6. Howard, J. C. J. exp. Med. 135, 185 (1972).

    Article  CAS  Google Scholar 

  7. Sachs, D. H. & Cone, J. L. J. exp. Med. 138, 1289 (1973).

    Article  CAS  Google Scholar 

  8. Hammerling, G. J., Deak, B. D., Mauve, G., Hammerling, U. & McDevitt, H. O., Immunogenetics 1, 68 (1974).

    Article  Google Scholar 

  9. Williams, R. M. & Moore, M. J. Trans. Proc. (in the press).

  10. Kunz, H. W. & Gill, T. J. J. Immunogenet. 1, 413 (1974).

    Article  Google Scholar 

  11. Cramer, D. V., Shonnard, J. W. & Gill, T. J. J. Immunogenet. 1, 421 (1974).

    Article  Google Scholar 

  12. Gasser, D. L. Adv. Immun. (in the press).

  13. Eijsvoogel, V. P., van Rood, J. J., Toit, E. D. & Schellekens, P. T. A. Eur. J. Immun. 2, 413 (1972).

    Article  CAS  Google Scholar 

  14. Van Rood, J. J., Leeuwen, A., Termijtelen, A. & Kenning, J. J. Transplant. Rev. 30, 122 (1976).

    CAS  PubMed  Google Scholar 

  15. Starz, O., Günther, E., Kohoutová, M. & Vojčik, L. Immunognetics (in the press).

Download references

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Authors and Affiliations

  1. Department of Immunology, Agricultural Research Council, Institute of Animal Physiology, Babraham, Cambridge, UK

    GEOFFREY W. BUTCHER & JONATHAN C. HOWARD

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  1. GEOFFREY W. BUTCHER
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  2. JONATHAN C. HOWARD
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BUTCHER, G., HOWARD, J. A recombinant in the major histocompatibility complex of the rat. Nature 266, 362–364 (1977). https://doi.org/10.1038/266362a0

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