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Is serum thymic factor of thymic origin?

Nature volume 272, pages 65–66 (1978)Cite this article

Abstract

THE role of the thymus in the control of the immune response is generally accepted, but the existence and the role of thymic hormones remain controversial1. Among factors claimed to be thymic hormones2–6, ‘facteur thymique serique’ (FTS) was not extracted from the thymus gland but from pig's blood6. This serum factor is a nonapeptide7, and poses the problem of whether FTS, or similar material, is present in the thymus1. By using non-denaturing techniques (4 °C ultrafiltration and chromatography) for the isolation of peptides and proteins from the thymus we have found that it does not.

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References

  1. Davies, A. J. S. Nature 266, 13 (1977).

    Article  ADS  Google Scholar 

  2. Goldstein, G. G. Nature 247, 11–14 (1974).

    Article  ADS  CAS  Google Scholar 

  3. Goldstein, G. G. et al. Proc. natn. Acad. Sci. U.S.A. 72, 11–15 (1975).

    Article  ADS  CAS  Google Scholar 

  4. Goldstein, A. L. et al. Proc. natn. Acad. Sci. U.S.A 74, 725–729 (1977).

    Article  ADS  CAS  Google Scholar 

  5. Kook, A. I., Yakur, Y. & Training, N. Cell. Immun. 19, 151–157 (1975).

    Article  CAS  Google Scholar 

  6. Bach, J. F., Dardenne, M., Pleau, J. M. & Bach, M. A. Ann. N.Y. Acad. Sci. 249, 186–210 (1975).

    Article  ADS  CAS  Google Scholar 

  7. Bach, J. F., Dardenne, M. & Pleau, J. M. Nature 266, 55–57 (1977).

    Article  ADS  CAS  Google Scholar 

  8. Bach, J. F. & Dardenne, M. Cell. Immun. 3, 1–10 (1972).

    Article  CAS  Google Scholar 

  9. Gershwin, M. E., Steinberg, A. D., Woody, J. N. & Ahmed, A. J. Immun. 115, 1444–1448 (1975).

    PubMed  CAS  Google Scholar 

  10. Hooper, J. A. et al. Ann. N.Y. Acad. Sci. 249, 125–144 (1975).

    Article  ADS  CAS  Google Scholar 

  11. Brand, A., Gilmour, D. G. & Goldstein, G. Nature 269, 597–598 (1977).

    Article  ADS  CAS  Google Scholar 

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Authors and Affiliations

  1. INSERM Unité 113, Hópital Saint-Antoine, 75571, Paris, Cedex XII, France

    N. KELEMEN, F. LASMOLES & G. MILHAUD

Authors
  1. N. KELEMEN
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  2. F. LASMOLES
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  3. G. MILHAUD
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KELEMEN, N., LASMOLES, F. & MILHAUD, G. Is serum thymic factor of thymic origin?. Nature 272, 65–66 (1978). https://doi.org/10.1038/272065a0

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