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Potential for variability through multiple gene products of bacteriophage ΦX174

Abstract

The small single-stranded DNA phages ΦX174 and S13 produce multiple products of certain phage genes, as observed by electrophoresis on SDS–polyacrylamide slab gels. Two A protein products, two A* products and four G products are observed. The multiple gene products may arise from multiple sites for initiation or termination of translation, or by protein modification. Some of the variant products may provide a substitute for heterozygosity without a concomitant increase in the size of the genome.

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Pollock, T., Tessman, I. & Tessman, E. Potential for variability through multiple gene products of bacteriophage ΦX174. Nature 274, 34–37 (1978). https://doi.org/10.1038/274034a0

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