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Immunofluorescence in osteoarthritis

Abstract

OSTEOARTHRITIS is widely regarded as a degenerative disorder1, but histological examination shows an inflammatory reaction in the synovium and subarticular marrow in many affected joints. In studies seeking to distinguish between inflammatory and degenerative cases, we have found and report here the presence of antibody in plasma cells in the synovium in osteoarthritis.

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References

  1. Byers, P. D. et al. Seminars in Arthritis and Rheumatism Vol 6, No. 3, 277–303 (Grune and Stratton, New York, 1977).

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  2. Glynn, L. E. Lancet i, 574–5 (1977).

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PRINGLE, J., BYERS, P. & BROWN, M. Immunofluorescence in osteoarthritis. Nature 274, 94 (1978). https://doi.org/10.1038/274094a0

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