Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Haploid cell cultures of Drosophila melanogaster

Abstract

EFFORTS to establish haploid animal cell lines have produced encouraging results only for the frog1,2 and cockroach3, the genetics of which are poorly understood. Attempts to use mouse teratocarcinoma, which would be more suitable in this respect, have failed4, perhaps because of the presence of recessive lethal genes4,5. I describe here a haploid cell line established from a mutant of Drosophila melanogaster. Because of its simple karyotype (n = 4), this line will provide valuable experimental material for somatic cell geneticists.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Freed, J. J. Exp. Cell Res. 26, 327–333 (1962).

    Article  CAS  Google Scholar 

  2. Freed, J. J. & Mezger-Freed, L. Proc. natn. Acad. Sci. U.S.A. 65, 337–344 (1970).

    Article  ADS  CAS  Google Scholar 

  3. Philippe, C. & Landureau, J. C. Exp. Cell Res. 96, 287–296 (1975).

    Article  CAS  Google Scholar 

  4. Iles, S. A., McBurney, M. W., Bramwell, S. R., Deussen, Z. A. & Graham, C. F. J. Embryol. exp. Morph. 34, 387–405 (1975).

    CAS  PubMed  Google Scholar 

  5. Subtelny, S. J. exp. Zool. 139, 263–305 (1958).

    Article  CAS  Google Scholar 

  6. Echalier, G. & Ohanessian, A. C. R. hebd. Séanc. Acad. Sci. 268, 1771–1773 (1969).

    CAS  Google Scholar 

  7. Stalker, H. D. Genetics 39, 4–34 (1954).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Murdy, W. H. & Carson, H. L. Am. Nat. 93, 355–363 (1959).

    Article  Google Scholar 

  9. Carson, H. L. Genetics 55, 157–171 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Sturtevant, A. H. Z. Wiss. Zool. 135, 323–356 (1929).

    Google Scholar 

  11. Bridges, C. B. Proc. natn. Acad. Sci. U.S.A. 11, 706–710 (1925).

    Article  ADS  CAS  Google Scholar 

  12. Bridges, C. B. Sciences 72, 405–406 (1930).

    Google Scholar 

  13. Hinton, C. W. & McEarchern, W. Dros. Inf. Serv. 37, 90 (1963).

    Google Scholar 

  14. Gans, M. Audit, C. & Masson, M. Genetics 81, 683–704 (1975).

    CAS  PubMed  PubMed Central  Google Scholar 

  15. Zalokar, M., Audit, C. & Erk, I. Devl Biol. 47, 419–432 (1975).

    Article  CAS  Google Scholar 

  16. Echalier, G. & Ohanessian, A. In Vitro 6, 162–172 (1970).

    Article  CAS  Google Scholar 

  17. Shields, G., Dubendorfer, A. & Sang, J. H. J. Embryol. exp. Morph. 33, 159–173 (1975).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

DEBEC, A. Haploid cell cultures of Drosophila melanogaster. Nature 274, 255–256 (1978). https://doi.org/10.1038/274255a0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue date:

  • DOI: https://doi.org/10.1038/274255a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing