Abstract
THE renal juxtaglomerular complex is conventionally considered to consist of the afferent and efferent glomerular arterioles, the macula densa of the distal tubule, and the interposed polar cushion region1. The afferent arteriolar wall contains myoepithelial cells characterised by the presence of multiple secretory-type cytoplasmic granules. It is widely accepted that such granules contain renin2, the hormone responsible for the production of angiotensin I from plasma renin substrate. We now report the finding of another potential secretory component of the juxtaglomerular complex, raising the possibility of unsuspected functional interactions in this region.
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RYAN, G., COGHLAN, J. & SCOGGINS, B. The granulated peripolar epithelial cell: a potential secretory component of the renal juxtaglomerular complex. Nature 277, 655–656 (1979). https://doi.org/10.1038/277655a0
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DOI: https://doi.org/10.1038/277655a0
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