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Monoclonal antibodies which recognize different cell types in the rat retina

Abstract

Seven monoclonal antibodies have been produced against a membrane preparation from adult rat retina. Three antibodies reacted with particular regions of rat photoreceptor cell surfaces: RET-P1 labelled the cell bodies, outer and inner segments (rods but not cones), RET-P2 labelled only outer segments and RET-P3 labelled only the cell bodies. Three antibodies reacted with glial cells; RET-G2 and RET-G3 were specific for Müller cells, RET-G1 also labelled glia elsewhere in brain. The seventh antibody (RET-N1) reacted with many types of neuronal cells.

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Barnstable, C. Monoclonal antibodies which recognize different cell types in the rat retina. Nature 286, 231–235 (1980). https://doi.org/10.1038/286231a0

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