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Actions of cholera toxin and the prevention and treatment of cholera

Nature volume 292, pages 413–417 (1981)Cite this article

Abstract

The drastic intestinal secretion of fluid and electrolytes that is characteristic of cholera is the result of reasonably well understood cellular and biochemical actions of the toxin secreted by Vibrio cholerae. Based on this understanding it is possible to devise new techniques for the treatment and prophylaxis of cholera to complement those based on fluid replacement therapy and sanitation.

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  1. Institute of Medical Microbiology, University of Göteborg, S-413 46, Göteborg, Sweden

    Jan Holmgren

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Holmgren, J. Actions of cholera toxin and the prevention and treatment of cholera. Nature 292, 413–417 (1981). https://doi.org/10.1038/292413a0

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