Abstract
Promoter function in yeast has been examined by obtaining revertants of a his3 promoter deletion in vivo. Events which provide a new promoter for the his3 gene include insertion of the transposable element Ty1, rearrangements of the plasmid vector, and chromosomal mutations. A role for dicentric chromosomes as a source of the plasmid rearrangements is discussed.
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Scherer, S., Mann, C. & Davis, R. Reversion of a promoter deletion in yeast. Nature 298, 815–819 (1982). https://doi.org/10.1038/298815a0
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DOI: https://doi.org/10.1038/298815a0
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