Abstract
Natural killer (NK) cells cloned in vitro have been transferred into NK-deficient hosts. These cells have been shown to have a role in the rejection of allogeneic bone marrow grafts, resistance to both radiation-induced thymic leukaemia and challenge with melanoma tumour cells. It appears that NK cells have an important role in immune surveillance.
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Warner, J., Dennert, G. Effects of a cloned cell line with NK activity on bone marrow transplants, tumour development and metastasis in vivo. Nature 300, 31–34 (1982). https://doi.org/10.1038/300031a0
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DOI: https://doi.org/10.1038/300031a0
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