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Molecular characterization of genome of a novel human T-cell leukaemia virus
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  • Published: 06 October 1983

Molecular characterization of genome of a novel human T-cell leukaemia virus

  • Irvin S. Y. Chen1,
  • Jami McLaughlin1,
  • Judith C. Gasson1,
  • Steven C. Clark2 &
  • …
  • David W. Golde 1 

Nature volume 305, pages 502–505 (1983)Cite this article

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Abstract

A novel human retrovirus (HTLV-II) was previously found associated with a T-cell variant of hairy-cell leukaemia. Molecular cloning demonstrates that the complete provirus genome is 8.8 kilobase pairs in size and is transmissible to uninfected cells. Two types of infectious deleted provirus were also characterized. The sequences of HTLV-II are distinct from those of HTLV-I.

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Author information

Authors and Affiliations

  1. Division of Hematology-Oncology, Department of Medicine, UCLA School of Medicine, Los Angeles, California, 90024, USA

    Irvin S. Y. Chen, Jami McLaughlin, Judith C. Gasson & David W. Golde

  2. The Genetics Institute, 225 Longwood Avenue, Boston, Massachusetts, 02115, USA

    Steven C. Clark

Authors
  1. Irvin S. Y. Chen
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  2. Jami McLaughlin
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  3. Judith C. Gasson
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  4. Steven C. Clark
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  5. David W. Golde
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Cite this article

Chen, I., McLaughlin, J., Gasson, J. et al. Molecular characterization of genome of a novel human T-cell leukaemia virus. Nature 305, 502–505 (1983). https://doi.org/10.1038/305502a0

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  • Received: 13 June 1983

  • Accepted: 09 August 1983

  • Issue date: 06 October 1983

  • DOI: https://doi.org/10.1038/305502a0

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