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Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes

Nature volume 308, pages 327–333 (1984)Cite this article

Abstract

DNA sequences of four human class II histocompatibility antigen α chain DNA sequences (derived from cDNA and genomic clones representing DC1α, DC4α, DXα and SBα) are presented and compared to DRα and to mouse I-Aα and I-Eα sequences. These data suggest possible mechanisms for the generation of polymorphism and the evolution of the DR, DC and SB families.

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Author notes

  1. Charles Auffray

    Present address: CNRS Institut d'Embryologie, Nogent-sur-Marne, 94130, France

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Harvard University, 7 Divinity Avenue, Cambridge, Massachusetts, 02138, USA

    Charles Auffray, James W. Lillie, David Arnot, Dario Grossberger, Dietmar Kappes & Jack L. Strominger

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  1. Charles Auffray
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  2. James W. Lillie
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  3. David Arnot
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  4. Dario Grossberger
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  5. Dietmar Kappes
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  6. Jack L. Strominger
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Auffray, C., Lillie, J., Arnot, D. et al. Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes. Nature 308, 327–333 (1984). https://doi.org/10.1038/308327a0

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