Abstract
Study design: Serum levels of carboxyterminal propeptide of type I collagen (PICP), osteocalcin (OC), carboxyterminal telopeptide of type I collagen (ICTP) and urinary levels of pyridinoline (Pyr) and deoxypyridinoline (Dpyr) were measured in patients with ossification of posterior longitudinal ligament of the spine (OPLL) and age-matched control subjects.
Objectives: To evaluate the efficacy of these biochemical markers of the patients with OPLL.
Setting: Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Methods: Spot urine and blood samples were obtained from 20 healthy males aged 45–78 (mean±SD; 63.0±11.5) and 22 male patients with OPLL aged 46–77 (mean±SD; 59.9±8.8), and serum levels of PICP, OC, ICTP and urinary levels of Pyr and Dpyr were measured.
Results: There were no significant difference in age, serum PICP, OC, ICTP, urinary Pyr and Dpyr levels between OPLL and control group.
Conclusion: Neither bone formation nor bone resorption was accelerated in the patients with OPLL.
Spinal Cord (2000) 38, 211–213
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Ishihara, C., Kushida, K., Takahashi, M. et al. The efficacy of biochemical markers in patients with ossification of posterior longitudinal ligament of the spine. Spinal Cord 38, 211–213 (2000). https://doi.org/10.1038/sj.sc.3100989
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DOI: https://doi.org/10.1038/sj.sc.3100989
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