Abstract
Study Design: Single subject (male, 34 years-of-age) case report.
Objectives: To describe a unique case of plasma cell granuloma (PCG) with simultaneous brain and spinal cord involvement.
Setting: Private hospital, capital city, Turkey.
Methods: The patient presented with headache and paraplega. T2 weighted MR images showed multiple hyperintense cerebral, cerebellar, brainstem and spinal cord lesions that enhanced homogeneously with contrast medium. The patient was operated on, and the two intramedullary spinal cord lesions at T11 and T12 were totally excised.
Results: After 3 months of an intense physiotherapy programme the patient was able to walk with help.
Conclusion: We report for the first time, the occurrence of multiple, simultaneous brain and intramedullary spinal cord plasma cell granulomas.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Anthony PP . Inflammatory pseudotumor (plasma cell granuloma) of the lung, liver and other organs Histopathology 1993 23: 501–503
Le March'hadour F, Fransen P, Labat-Moleur F, Passagia JG, Pasquier B . Intracranial plasma cell granuloma: A report of four cases Surg Neurol 1994 42: 481–488
Hsiang J, Moorhouse D, Barba D . Multiple plasma cell granuloma of the central nervous system: A case report Neurosurgery 1994 35: 744–747
Malhotra V et al. An unusual case of plasma cell granuloma involving lung and brain Indian J Cancer 1991 28: 223–227
Eimoto T, Yanaka M, Kurosana M, Ikeya F . Plasma cell granuloma of the spinal cord meninges. Report of a case Cancer 1978 41: 1929–1936
Lee M, Epstein FJ, Rezai AR, Zagzag D . Nonneoplastic intramedullary spinal cord lesions mimicking tumors Neurosurgery 1998 43: 788–794
Bando T et al. Pulmonary plasma cell granuloma improves with corticosteroid therapy Chest 1994 105: 1574–1575
Fukunga A et al. Plasma cell granuloma extending from the extracranial to the intracranial space associated with Epstein-Barr virus infection Neurol Med Chir 1998 38: 292–296
Cannella DM, Prezyna AP, Kapp J . Primary intracranialplasma-cell granulma J Neurosurg 1988 68: 785–788
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kılınç, M., Ertürk, İ., Uysal, H. et al. Multiple plasma cell granuloma of the central nervous system: a unique case with brain and spinal cord involvement. Case report and review of literature. Spinal Cord 40, 203–206 (2002). https://doi.org/10.1038/sj.sc.3101271
Published:
Issue date:
DOI: https://doi.org/10.1038/sj.sc.3101271
Keywords
This article is cited by
-
Imaging and pathological findings of intramedullary inflammatory pseudotumour in a miniature dachshund: a case report
BMC Veterinary Research (2019)
-
Intracranial multifocal plasma cell granuloma: a case with multiple operations without recurrence of surgically removed lesions
Acta Neurochirurgica (2016)
-
Primary intracranial plasma cell granulomas presenting as malignant neoplasms
Journal of Neuro-Oncology (2012)
-
Intradural extramedullary spinal inflammatory myofibroblastic tumor: case report and literature review
European Spine Journal (2011)
-
Inflammatory myofibroblastic tumor in the intradural extramedullary space of the lumbar spine with spondylolisthesis: case report and review of the literature
European Spine Journal (2010)
