Abstract
Study design:
A case report.
Objectives:
To report a rare case of extension of edema and hemorrhage from initial C4–5 spinal injury to the medulla oblongata.
Setting:
Center for Spinal Disorders and Injuries, Bibai Rosai Hospital, Japan.
Methods:
A 68-year-old man with ossification of the posterior longitudinal ligament (OPLL) had sustained tetraplegia after tumbling over a stone. Initially, the patient was diagnosed with an acute C4–5 spinal cord injury without radiological abnormalities and was treated conservatively. At 7 h after the injury, the patient had an ascending neurological deficit, which required respiratory assistance. Magnetic resonance imaging revealed a marked swelling of the spinal cord above C4–5 extending to the medulla oblongata.
Results:
Retrospective radiological assessment revealed that the spine was unstable at the injury level because of discontinuities in both anterior and posterior longitudinal ligaments. There was also signal intensity change within the retropharyngeal space at the C4–5 intervertebral disc. This injured segment was highly vulnerable to post-injury dynamic stenosis and easily sustained secondary neural damage.
Conclusions:
This case report emphasizes a careful radiological assessment of latent structural instability in patients with OPLL in order to detect and prevent deteriorative change in the spinal cord.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Famer J et al. Neurologic deterioration after cervical spinal cord injury. J Spinal Disord 1998; 11: 192–196.
Marshall LF, Knowlton S, Garfin SR . Deterioration following spinal cord injury: a multicenter study. J Neurosurg 1987; 66: 400–404.
Mahale YJ, Silver JR . Progressive paralysis after bilateral facet dislocation of the cervical spine. J Bone Joint Surg [Britain] 1992; 74: 219–223.
Benzel EC et al. Magnetic resonance imaging for the evaluation of patients with occult cervical spine injury. J Neurosurg 1996; 85: 824–829.
Flanders AE et al. Acute cervical spine trauma: correlation of MR Imaging findings with degree of neurologic deficit. Neuroradiology 1990; 177: 25–33.
Bracken MB et al. A randomized controlled trial of methylprednisolone or naloxone in the treatment of ascute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study. N Engl J Med 1990; 322: 1405–1411.
Banick N, Hogan E, Hsu C . The multimolecular cascade of spinal cord injury. Neurochem Pathol 1987; 7: 57–77.
Tator CH, Fehlings MG . Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. J Neurosurg 1991; 75: 15–26.
Lu K et al. Delyed apnea in patients with mid-to lower cervical spinal cord injury. Spine 2000; 25: 1332–1338.
Fox MW, Onofrio BM, Kilgore JE . Neurological complications of ankylosing spondylitis. J Neurosurg 1993; 78: 871–878.
Paley D et al. Fractures of the spine in diffuse idiopathic skeletal hyperostosis. Clin Orthop 1991; 267: 22–32.
Bohlman HH . Acute fractures and dislocations of the cervical spine. J Bone Joint Surg [America] 1979; 61: 1119–1142.
Reid DC et al. Etiology and clinical course of missed spine fractures. J Trauma 1987; 27: 980–986.
Ito T et al. Traumatic spinal cord injury: a neuropathological study on the longitudinal spreading of the lesions. Acta Neuropathol (Berlin) 1997; 93: 13–18.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sudo, H., Taneichi, H. & Kaneda, K. Secondary medulla oblongata involvement following middle cervical spinal cord injury associated with latent traumatic instability in a patient with ossification of the posterior longitudinal ligament. Spinal Cord 44, 126–129 (2006). https://doi.org/10.1038/sj.sc.3101803
Published:
Issue date:
DOI: https://doi.org/10.1038/sj.sc.3101803


