A new development in gel electrophoresis allows investigators to fractionate and analyse DNA species from 10,000 to more than a million base pairs.
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References
Schwartz, D.C. et al. Cold Spring Harb. Symp. quant. Biol. 47, 189–195 (1983).
Schwartz, D.C. & Cantor, C.R. Cell 37, 67–75 (1984).
Carle, G.F. & Olson, M.V. Nucleic Acids Res. 12, 5647–5664 (1984).
Smith, C.L., Warburton, P.W., Gaal, A. & Cantor, C.R. in Genetic Engineering 8 (eds Setlow, J.K. & Hollaender, A.) (Plenum, New York, in the press).
Carle, G.F. & Olson, M.V. Proc. natn. Acad. Sci., U.S.A. 82, 3756–3760 (1985).
Van der Ploeg, L.H.T., Schwartz, D.C., Cantor, C.R. & Borst, P. Cell 37, 77–84 (1984).
Spithill, T.W. & Samaras, N. Nucleic Acid Res. 13, 4155–4169 (1985).
Kemp, D.J. et al. Nature 315, 347–350 (1985).
Smith, C.L. et al. Meth. Enzym. (in the press).
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Smith, C., Cantor, C. Pulsed-field gel electrophoresis of large DNA molecules. Nature 319, 701–702 (1986). https://doi.org/10.1038/319701a0
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DOI: https://doi.org/10.1038/319701a0
