Figure 2 | Gene Therapy

Figure 2

From: Direct transfection and activation of human cutaneous dendritic cells

Figure 2

Biolistic delivery of DNA does not affect the morphology of migratory DCs from human epidermal/dermal explants and they contain intracytoplasmic gold particles. (a) Cytospin preparation shows skin migratory DCs containing intracellular gold particles (arrows) (May–Grünwald-Giemsa, ×400) (scale bar, 5 μm). (b) Ultrastructural analysis of skin migratory DCs (arrowheads) from gene gun transfected epidermal/dermal explants, one of them with one intracytosolic 1 μm gold particle (arrow and insert) (TEM, ×9000, insert ×19 000).

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