Abstract
Null mutations of glass specifically remove photo-receptor cells, leaving other cell types intact. We have isolated the glass gene and have shown that its transcript encodes a putative protein of 604 amino acids with five zinc-fingers. The glass product may be a transcription factor required for the development of a single neuronal cell type.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Bolwig, N. Vidensk. Meddr. dansk neturh. Foren. 109, 80–212 (1946).
Goodman, L. J. in Handbook of Sensory Physiology Vol. II(6c), 201–286 (Springer, New York, 1981).
Dietrich, W. Z. wiss. Zool. 92, 465–539 (1909).
Fujita, S. C. et al. Proc. natn. Acad. Sci. U.S.A. 79, 7929–7933 (1982).
Jan, L. Y. & Jan, Y. N. Proc. natn. Acad. Sci. U.S.A. 79, 2700–2704 (1982).
Zuker, C. S., Cowman, A. F. & Rubin, G. M. Cell 40, 851–858 (1985).
Van Vactor, D. et al. Cell 52, 281–290 (1988).
Montell, C. & Rubin, G. M. Cell 52, 757–772 (1988).
Montell, C. et al. Science 230, 1040–1043 (1985).
Bridges, C. B. & Morgan, T. H. in The Third Chromosome Group of Mutant Characters of Drosophila melanogaster 327, 188–190 (Carnegie Inst. Wash., 1923).
Meyerowitz, E. M. & Kankel, D. R. Devl Biol. 62, 112–142 (1978).
Ready, D. F., Tomlinson, A. & Lebovitz, R. M. in Development of Order in the Visual System (eds Hilfer, S. R. & Sheffield, J. B.) 97–125 (Springer, New York, 1986).
Miller, J., McLachlan, A. D. & Klug, A. EMBO J. 4, 1609–1614 (1985).
Kadonaga, J. T. et al. Cell 51, 1079–1090 (1987).
Klug, A. & Rhodes, D. Trends biochem. Sci. 12, 464–469 (1987).
Steller, H., Fischbach, K.-F. & Rubin, G. M. Cell 50, 1139–1153 (1987).
Lawrence, P. A. & Green, S. M. Devl Biol. 71, 142–152 (1979).
Ready, D. F., Hanson, T. E. & Benzer, S. Devl Biol. 53, 217–240 (1976).
Tomlinson, A. J. Embryol. exp. Morphol. 89, 313–331 (1985).
Tomlinson, A. & Ready, D. F. Devl Biol. 120, 366–376 (1987).
Tomlinson, A. et al. Cell 51, 143–150 (1987).
Tomlinson, A., Kimmel, B. E. & Rubin, G. M. Cell 55, 771–784 (1988).
Searles, L. L. et al. Cell 31, 585–592 (1982).
Levis, R., Hazelrigg, T. & Rubin, G. M. Science 229, 558–561 (1985).
Gailey, D. A. & Hall, J. C. Genetics 121, 773–785 (1989).
Rubin, G. M. & Spradling, A. C. Science 218, 348–353 (1982).
Cavener, D. R. Nucleic Acids Res. 15, 1353–1361 (1987).
Melton, D. A. et al. Nucleic Acids Res. 12, 7035–7056 (1984).
McKnight, S. L. & Kingsbury, R. Science 217, 316–324 (1982).
Hultmark, D., Klemenz, R. & Gehring, W. J. Cell 44, 429–438 (1986).
Rosenberg, U. B. et al. Nature 319, 336–339 (1986).
Schuh, R. et al. Cell 47, 1025–1032 (1986).
Ollo, R. & Maniatis, T. Proc. natn. Acad. Sci. U.S.A. 84, 5700–5704 (1987).
Jäckle, H. et al. Nature 324, 668–670 (1986).
Stillman, D. J. et al. EMBO J. 7, 485–494 (1988).
Ciriacy, M. Molec. Gen. Genet. 138, 157–164 (1975).
Gaul, U. et al. Cell 50, 639–647 (1987).
Chavrier, P. et al. Molec. cell. Biol. 8, 1319–1326 (1988).
Kinzler, K. W. et al. Nature 332, 371–374 (1988).
Tomlinson, A. & Ready, D. F. Devl Biol. 123, 264–275 (1987).
Dequin, R., Saumweber, H. & Sadat, J. W. Devl Biol. 104, 37–48 (1984).
Eugene, O., Yund, M. A. & Fristrom, J. W. Tissue Culture Assoc. Manual 5, 1055–1062 (1979).
Messing, J. Meth. Enzymol. 101, 20–78 (1983).
Sanger, F., Nicklen, S. & Coulsen, A. R. Proc. natn. Acad. Sci. U.S.A. 74, 5463–5467 (1977).
Bankier, A. T. & Barrell, B. G. in Techniques in the Life Sciences, B5, Nucleic Acid Biochemistry, (B508) 1–34 (ed. Flavel, R. A.) (Elsevier, Ireland Ltd, Shannon and New York, 1983).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Moses, K., Ellis, M. & Rubin, G. The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells. Nature 340, 531–536 (1989). https://doi.org/10.1038/340531a0
Received:
Accepted:
Issue date:
DOI: https://doi.org/10.1038/340531a0
This article is cited by
-
Glass confers rhabdomeric photoreceptor identity in Drosophila, but not across all metazoans
EvoDevo (2019)
-
Nuclear receptors connect progenitor transcription factors to cell cycle control
Scientific Reports (2017)
-
Regulation of sleep plasticity by a thermo-sensitive circuit in Drosophila
Scientific Reports (2017)
-
The commonly used eye-specific sev-GAL4 and GMR-GAL4 drivers in Drosophila melanogaster are expressed in tissues other than eyes also
Journal of Genetics (2015)
-
Drosophila melanogaster as a model organism for Alzheimer’s disease
Molecular Neurodegeneration (2013)