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Immunological modulation and evasion by helminth parasites in human populations

Nature volume 365, pages 797–805 (1993)Cite this article

Abstract

Helminth parasites are highly prevalent in human communities in developing countries. In an endemic area an infected individual may harbour parasitic worms for most of his or her life, and the ability of these infections to survive immunological attack has long been a puzzle. But new techniques are starting to expose the diverse mechanisms by which these agents modulate or evade their hosts' defences, creating a dynamic interaction between the human immune system and the parasite population.

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  1. Wellcome Research Centre for Parasitic Infections, Departments of Biology (R.M.M., D.A.P.B. and R.M.A.) and Biochemistry (M.E.S. and D.F.S.), Imperial College of Science, Technology and Medicine, Prince Consort Road, London, SW7 2BB, UK

    Rick M. Maizels, Don A. P. Bundy, Murray E. Selkirk, Deborah F. Smith & Roy M. Anderson

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Maizels, R., Bundy, D., Selkirk, M. et al. Immunological modulation and evasion by helminth parasites in human populations. Nature 365, 797–805 (1993). https://doi.org/10.1038/365797a0

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