Table 1 Levels of each-strand EV RNA and TLR4 mRNA, immunohistochemistry of EV capsid protein VP1 and TLR4, and clinical outcomes in DCM patients
Patient No. | Age (years) | Sex | Levels of EV RNA and TLR4 mRNA | Immunohistochemistry | LVEF (%) | LVESD (mm) | |||
|---|---|---|---|---|---|---|---|---|---|
Plus-strand | Minus-strand | TLR4 | VP1 | TLR4 | |||||
1 | 40 | M | 3.22 | 0.40 | 0.16 | + | + | 22 | 48 |
2 | 22 | M | 3.54 | 2.36 | 0.47 | + | + | 22 | 64 |
3 | 56 | M | 5.21 | 2.89 | 0.66 | + | + | 24 | 55 |
4 | 49 | M | 0.56 | 0.56 | 0.13 | − | + | 26 | 49 |
5 | 68 | M | — | — | 0.06 | − | − | 35 | 49 |
6 | 68 | M | 1.40 | 1.56 | 0.25 | + | + | 29 | 62 |
7 | 52 | M | 3.15 | 2.98 | 0.32 | + | + | 30 | 56 |
8 | 22 | F | 0.51 | 0.39 | 0.47 | − | + | 25 | 51 |
9 | 48 | M | 2.42 | 2.62 | 0.10 | + | + | 22 | 56 |
10 | 70 | M | 3.48 | 1.86 | 0.81 | + | + | 22 | 54 |
11 | 65 | F | 3.75 | 2.68 | 0.43 | + | + | 28 | 57 |
12 | 66 | F | 7.34 | 6.34 | 0.58 | + | + | 22 | 56 |
13 | 67 | M | 5.31 | 4.55 | 0.66 | + | + | 33 | 66 |
14 | 65 | M | 1.77 | 1.42 | 0.53 | + | + | 27 | 50 |
15 | 50 | F | 0.36 | 0.29 | 0.13 | + | + | 38 | 52 |
16 | 42 | M | 1.01 | 0.94 | 0.19 | + | + | 33 | 46 |
17 | 39 | M | 4.82 | 5.09 | 0.88 | + | + | 20 | 64 |
18 | 73 | M | 1.61 | 1.77 | 0.13 | + | + | 28 | 49 |
19 | 38 | F | 0.27 | 0.46 | 0.19 | + | + | 33 | 49 |
20 | 66 | M | — | — | 0.08 | − | + | 39 | 50 |
21 | 54 | M | — | — | 0.11 | − | + | 42 | 51 |
22 | 15 | M | — | — | 0.10 | − | + | 45 | 46 |
23 | 41 | M | — | — | 0.19 | − | − | 36 | 49 |
24 | 65 | M | — | — | 0.11 | − | − | 43 | 48 |
25 | 70 | M | — | — | 0.02 | − | − | 39 | 47 |
26 | 42 | F | — | — | 0.01 | − | − | 38 | 48 |
27 | 65 | M | — | — | 0.02 | − | − | 44 | 48 |
28 | 70 | M | — | — | 0.01 | − | − | 41 | 47 |
29 | 16 | M | — | — | 0.02 | − | − | 39 | 48 |
30 | 25 | M | — | — | 0.10 | − | + | 42 | 46 |
31 | 28 | M | — | — | 0.11 | − | + | 38 | 47 |
32 | 55 | F | — | — | 0.07 | − | − | 45 | 49 |
33 | 43 | F | — | — | 0.01 | − | − | 46 | 47 |
34 | 20 | M | — | — | 0.11 | − | + | 21 | 49 |
35 | 28 | M | — | — | 0.27 | − | + | 27 | 54 |
36 | 64 | M | — | — | 0.28 | − | + | 30 | 55 |
37 | 66 | M | — | — | 0.33 | − | + | 32 | 59 |
38 | 53 | M | — | — | 0.22 | − | + | 19 | 60 |
39 | 48 | F | — | — | 0.04 | − | − | 39 | 48 |
40 | 49 | M | — | — | 0.05 | − | − | 37 | 49 |
41 | 68 | F | — | — | 0.02 | − | − | 38 | 51 |
42 | 29 | M | — | — | 0.10 | − | − | 41 | 45 |
43 | 73 | M | — | — | 0.19 | − | − | 44 | 45 |
44 | 66 | M | — | — | 0.22 | − | − | 29 | 49 |
45 | 62 | F | — | — | 0.03 | − | − | 37 | 49 |
46 | 31 | F | — | — | 0.09 | − | − | 39 | 52 |
47 | 44 | M | — | — | 0.44 | − | + | 18 | 55 |
48 | 60 | M | — | — | 0.30 | − | + | 22 | 49 |
49 | 50 | M | — | — | 0.23 | − | + | 24 | 50 |
50 | 59 | M | — | — | 0.58 | − | + | 19 | 59 |
51 | 53 | M | — | — | 0.15 | − | + | 29 | 49 |
52 | 66 | M | — | — | 0.39 | − | + | 26 | 53 |
53 | 35 | M | 0.85 | 0.42 | 0.99 | + | + | 11 | 59 |
54 | 39 | F | — | — | 0.01 | − | − | 36 | 52 |
55 | 55 | F | — | — | 0.02 | − | − | 44 | 50 |
56 | 41 | M | — | — | 0.03 | − | − | 43 | 50 |
