Table 2 Cytotoxic activity of CMCs derived from WB-+/+, WB-mi/mi, WBB6F1-+/+ or WBB6F1-mi/mi mice

From: Strain-dependent inhibitory effect of mutant mi-MITF on cytotoxic activities of cultured mast cells and natural killer cells of mice

E/T ratio

Specific 51Cr release (%) by 18 h coculturea

 

WB-+/+

WB-mi/mi

WBB6F1-+/+

WBB6F 1 -mi/mi

50

12.6±0.8 (3)

11.6±1.0 (3)

11.3±1.0 (3)

9.7±1.3 (3)

100

17.2±1.0 (3)

15.0±1.3 (3)

14.9±1.2 (3)

13.9±1.0 (3)

250

21.7±1.0 (3)

20.2±1.3 (3)

20.0±1.2 (3)

18.7±1.2 (3)

  1. E/T ratio indicates the ratio of CMCs to YAC-1 cells.
  2. aMean±s.e. The number of independent assays are shown within parentheses. Significant difference (P<0.05 by t-test) was not detectable between values of +/+ and mi/mi mice of the same genetic background.
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