Table 6 Proportion of NK1.1+ cells and LGLs in spleen mononuclear cells and in cultured spleen cells of B6-+/+, B6- mi/mi, WB-+/+, WB- mi/mi, WBB6F1-+/+ and WB B6F1-mi/mi mice

From: Strain-dependent inhibitory effect of mutant mi-MITF on cytotoxic activities of cultured mast cells and natural killer cells of mice

Origin of spleen cells

Proportion of NK1.1+ cells (%)a

Proportion of LGLs (%)a

 

Spleen mononuclear cells b

Cultured spleen cells

Spleen mononuclear cells b

Cultured spleen cells

B6-+/+

2.1±0.3 (3)

82±2 (3)

1.3±0.2 (3)

75±5 (4)

B6-mi/mi

1.8±0.3 (3)

82±1 (3)

<0.1 (3)*

6±3 (4)*

WB-+/+

1.9±0.5 (3)

82±3 (3)

1.0±0.1 (3)

78±3 (4)

WB-mi/mi

2.0±0.3 (3)

81±3 (3)

0.8±0.3 (3)

74±4 (4)

WBB6F1-+/+

2.1±0.4 (3)

80±2 (3)

1.1±0.3 (3)

78±5 (4)

WBB6F1-mi/mi

2.0±0.2 (3)

81±2 (3)

0.9±0.2 (3)

76±4 (4)

  1. aMean±s.e. (%). Then umber of independent evaluations are shown within parentheses.
  2. bSpleen cells were obtained from nontreated mice.
  3. *P<0.01 by t test when compared with the value of +/+ mice of the same genetic background.
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