Figure 4

Micrographs showing toluidine blue-stained sections of skeletal muscle, lung and spleen of W^f/W^f and BMMC engrafted W^f/W^f mice. No mast cells are detectable in the skeletal muscle, lung or spleen of W^f/W^f mice (a, c and e, respectively). (b) A metachromatic-stained mast cell is visible (arrow) in the connective tissue surrounding skeletal muscle of BMMC engrafted W^f/W^f. (d) Three metachromatic-stained mast cells (arrows) are visible in the lung of BMMC engrafted W^f/W^f. (f) Several metachromatic mast cells (arrows) are located in the spleen of BMMC engrafted W^f/W^f. n≥4 for all groups. Magnification × 400. Scale bar=50 μm.