Figure 1 | Laboratory Investigation

Figure 1

From: SYT, a partner of SYT-SSX oncoprotein in synovial sarcomas, interacts with mSin3A, a component of histone deacetylase complex

Figure 1

Interaction of SYT or SYT-SSX with histone deacetylase complex proteins. (a) SYT and the variant with 31 amino acids (SYT(−31) and SYT(+31), respectively) showed interaction with mSin3A in yeast two-hybrid filter assay. (b) Intensity of the interaction is shown as β-galactosidase activity by yeast two-hybrid liquid culture assay. (c) SYT-SSX proteins showed less interaction with mSin3A.

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