Figure 6 | Laboratory Investigation

Figure 6

From: SYT, a partner of SYT-SSX oncoprotein in synovial sarcomas, interacts with mSin3A, a component of histone deacetylase complex

Figure 6

Effect of mSin3A on the transcriptional activity mediated by SYT and hBRM/BRG1. The indicated expression vectors (hBRM, BRG1 and mSin3A) were transfected into HEK293T cells with GAL4-luciferase reporter plasmid (pRF-Luc) and GAL4-fused SYT N-terminal (1–93) plasmid, pCMV-BD-SYT-N. Transfection efficiency was normalized using dual-luciferase system. Error bars indicate the standard deviation obtained from three independent assays. GAL4-SYT-N, pCMV-BD-SYT-N.

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