Table 4 Infection by PCR in heart from immunocompetent (IC) or transiently (TISP) or permanently (IS) immunosuppressed NHPs inoculated with B. burgdorferi N40 by needle or by tick-bite
NHP ID | Strain | Inoculation | Immunosuppression | 16s RT-PCR or PCR-ELISA (OspA/B) | |||
|---|---|---|---|---|---|---|---|
Aorta | Atrium | Ventricle | Apex | ||||
TO26 | BbN40 | Needle | IC-long term | − | − | nd | − |
TO29 | IC | nd | nd | nd | nd | ||
PAX40 | IC | nd | nd | nd | nd | ||
TO32 | IC | − | nd | nd | − | ||
E520 | IC | + | +/− | nd | − | ||
E518 | BbN40 | Needle | IC-short term | nd | − | nd | nd |
M14 | IC | − | − | − | − | ||
M15 | IC | − | − | − | − | ||
23Z | IC | nd | + | nd | nd | ||
E680 | IC | − | − | nd | − | ||
1616 | IC | nd | − | nd | nd | ||
652 | BbN40 | Needle | IS | + | + | + | + |
1538 | IS | nd | + | nd | + | ||
Z1 | IS | nd | + | nd | + | ||
PAX219 | IS | nd | + | nd | + | ||
1614 | IS | nd | + | nd | + | ||
30794 | IS | + | + | + | + | ||
372 | IS | + | + | + | + | ||
099 | BbN40 | Needle | TISP | nd | nd | + | nd |
177 | TISP | nd | nd | + | + | ||
199 | TISP | + | nd | nd | nd | ||
383 | TISP | + | nd | nd | nd | ||
154 | BbN40 | Tick | TISP | + | + | nd | nd |
192 | TISP | + | + | nd | nd | ||
211 | TISP | + | + | + | + | ||
242 | TISP | + | nd | nd | nd | ||
