Figure 4
From: MDM2 expression in EBV-infected nasopharyngeal carcinoma cells
Western blot analysis of MDM2 protein in NPC-TW01 cells, which were transfected with wt and mt p53 genes separately. (a) Lane 1: NPC-TW01 cells transfected with wt p53 gene; lane 2: NPC-TW01 cells transfected with mt p53 gene. The 90 kDa band of MDM2 in lane 1 is much stronger than that in lane 2. The 55 kDa band of α-tubulin reveals similar staining intensity in both lanes 1 and 2. (b) Densitometry analysis reveals a 5.1-fold higher MDM2 protein expression in wt p53-transfected NPC cells (lane 1) than mt p53-transfected cells (lane 2).
