Figure 1 | Laboratory Investigation

Figure 1

From: Reduced expression of IL-12 receptor β2 and IL-18 receptor α genes in natural killer cells and macrophages derived from B6-mi/mi mice

Figure 1

Expression of IL-12R and IL-18R genes in NK cells that were derived from B6-+/+, B6-mi/mi, or B6-tg/tg mice. (a) Expression of IL-12Rβ1, IL-12Rβ2 IL-18Rα, and IL-18Rβ genes in freshly isolated NK 1.1+ cells derived from B6-+/+, B6-mi/mi, or B6-tg/tg mice was examined, as measured by RT-PCR. Three independent experiments were performed, with comparable results: a representative experiments is shown. (b) Flow cytometric analysis of the expression of IL-12Rβ2 and IL-18Rα genes in freshly isolated NK 1.1+ cells with or without IFN-γ treatment that were derived from B6-+/+ or B6-mi/mi mice. Three independent experiments were performed, with comparable results: a representative experiments is shown.

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