Figure 3 | Laboratory Investigation

Figure 3

From: Reduced expression of IL-12 receptor β2 and IL-18 receptor α genes in natural killer cells and macrophages derived from B6-mi/mi mice

Figure 3

IFN-γ production by NK cells and macrophages that were derived from B6-+/+, or B6-mi/mi mice. Freshly isolated NK 1.1+ cells (a), cultured NK cells (b), peritoneal macrophages (c), and cultured Mac-1+ cells (d) were cultured with IL-12, IL-18, or IL-12 plus IL-18 for 5 h. Cultured NK cells (b) and cultured Mac-1+ cells (d) were also cultured in the presence of PMA-ionomycin. The culture supernatants were subjected to ELISA.

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