Table 3 ATM and ATR mutations in PAL cell lines
From: Alterations of DNA damage-response genes ATM and ATR in pyothorax-associated lymphoma
Cell lines | ATM | ATR | ||||
|---|---|---|---|---|---|---|
Nucleotide change | Predicted effect | Frequency of mutation-positive clones (%) | Nucleotide change | Predicted effect | Frequency of mutation-positive clones (%) | |
OPL-1 | T826G | Phe → Val | 50 | WT | — | — |
OPL-2 | WT | — | — | Exon 46/47 ins 137 bp | Frameshift | 40 |
OPL-3 | Exon 8 del 22 bp | Frameshift | 67 | WT | — | — |
OPL-4 | Del exon 33, 34+exon 37/38 ins 9 bp | Frameshift | 60 | WT | — | — |
Del exon 62+ins 72 bp | Frameshift | 33 | ||||
OPL-5 | Del exon 34 | Frameshift | 33 | WT | — | — |
OPL-7 | WT | — | — | WT | — | — |
Deglis | WT | — | — | WT | — | — |
Pal-1 | C9110T | Pro → Leu | 60 | T7637C | Val → Ala | 25 |
